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ICMR provides comprehensive view of phytochemical reference standards of selected medicinal plants
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Nandita Vijay, Bengaluru
April 01 , 2017
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ICMR is offering a comprehensive view of phytochemical reference
standards of selected Indian medicinal plants. It highlights the
isolation and complete characterization of PRS from commonly used
selected medicinal plants.
The 4th volume of the book released by
medicinal plants division of ICMR presents monographs of 30
phytochemical reference standard compounds. It helps the stakeholders to
develop pharmacopoeial standard further to provide quality raw
material.
As the importance of natural products continue to
increase, so will the need of reference substances for herbal products,
phytochemical markers or the phytochemical reference standard (PRS),
said Dr. DBA Narayana, chairman, Ayurvidye Trust, Bengaluru who reviewed
the book.
“This volume presents the isolation and complete
characterization of PRS from commonly used selected India medicinal
plants. Compilation presents generic and IUPAC name, structure of PRS,
photographs of the parts used, occurrence of the PRS in other plants as
reported in literature have also been included. Information on simple
method for isolation of PRS and any modification done in the methods
available in the literature has been reported,” he added.
Quantification
of PRS in the selected plant part has been illustrated.
Characterization using physico-chemical and spectral data including
UV-Vis, C NMR, IR, H NMR has been presented extensively. Original
spectra and their interpretation have been included. TLC, HPLC, HPTLC,
Gas Chromatography studies have been performed and are given along with
their representative chromatograms. Chromatographic finger printing of
plant material with reference PRS have been given. Adequate
bibliographic references have been provided which are useful, he noted.
With
this 4th volume being published monographs of 120 PRS from commonly
used Indian medicinal plants have been characterized. This volume
includes in the appendices materials and methods, extraction methods,
separation techniques used. Additionally this volume lists 90 monographs
from the earlier volumes, indices on chemical constituents and
botanical names of plants. Spectral data required for correct
identification and characterization are illustrated in a methodical
manner.
ICMR and its medicinal plants division needs to be
complimented for bringing this 4th volume. With more and more herbs and
their extracts getting used in products either as drugs or supplements/
nutraceuticals or used in cosmetic products on the increase need for
globally acceptable quality standards will become centre of discussions
and regulatory requirement, said Dr. Narayana.
This book serves a
great purpose as it provides rich scientific information and
methodologies for innovators and manufacturers to develop such
specifications. The TLC profile information in this book can itself
provide a simple tool in this direction. Adoption of these methods can
add value to generate claims support data demonstrating addition of
herbal materials into various products. Both industrial R&D in this
sector and academic institutions must own this series of ICMR
publications.
The Council in future editions may consider using
good quality map-litho or sunlit bond type of papers and avoid using art
papers to reduce the weight of this book and make them easy to handle.
In addition ICMR should also consider digitizing such publications so
that online search is possible, said Dr. Narayana. The hard bound with
jacket, 415 pages, is priced for Inland at Rs.1,750 and Foreign at US$ 76.
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